FGF2 and benign prostatic hyperplasia: Accordingly, in human BPH stromal cells, AR activation by DHT inhibited TNFα, LPS, or CD4 (+) T cell-induced secretion of inflammatory/growth factors, including interleukin (IL)-6, IL-8, and basic fibroblast growth factor (bFGF), by blocking the nuclear translocation of the nuclear factor kappa-B (NF- κB) (24).