PCSK9 and metabolic dysfunction-associated steatohepatitis: Based on these studies, we aimed to assess sex-specific differences in inflammation, fibrosis, and cholesterol metabolism, including PCSK9 expression across different tissues in a non-obese and non-alcoholic model of NASH in middle-aged C57Bl/6J mice, which might better resemble the human condition that occurs in the middle-aged and elderly population.