Rodriguez-Carrio J et al. reported reduced numbers of angiogenic T cells and endothelial progenitor cells in RA patients32, but another study found an elevated percentage of circulating angiogenic T cells that positively correlated with the percentage of endothelial progenitor cells in RA patients, which regulated VEGF levels through Akt signaling with CD14733. Here, AKT1 is linked to rheumatoid arthritis.