To determine whether Poldip2 regulates the expression of leukocyte adhesion molecules, brains from Poldip2+/+ and Poldip2+/− mice were harvested 24 h after cerebral ischemia induction and E-selectin, P-selectin, ICAM-1 and VCAM-1 mRNA levels were measured. Here, POLDIP2 is linked to brain ischemia.