When examining the top differentially expressed proteins/phosphoproteins from the RPPA across the three NSCLC cell lines (Supplemental Figs. 2, 3, and 4) in the three different model systems, TMES, xenograft, and 2D static culture, there is an increase in BAD pS112 and a decrease in cleaved caspase 3. Here, CASP3 is linked to non-small cell lung carcinoma.