KDM4C and hepatocellular carcinoma: To evaluate the effects of GASC1 on in vitro cell proliferation and in vivo tumor growth, we first determined the endogenous levels of GASC1 in various HCC cell lines (Supplementary Fig. 1b, c) and selected a few of them as GASC1High (Hep3B and MHCC-97H) and GASC1Low cell lines (Huh7 and PLC/PRF/5).