MYC and cancer: With respect to alternate targeting of Myc in Myc-dependent neoplasms, approaches to treat Myc-deregulated cancer are mostly fall into five catagories: (1) targeting MYC transcription; (2) targeting MYC mRNA translation; (3) targeting Myc stability; (4) targeting Myc–Max interaction; (5) targeting accessibility of Myc to downstream genes.