The serum cytokine data are in agreement with the report by Roth et al,10 in which IL-6 and IL-8 decreased when TILs caused tumor shrinkage (figure 5H), and other cytokines (interferonalpha (IFN-α), TNF-α (tumornecrosis factor alpha), CCL5 and IL-10) were positively related to the T cells (figure 5H). Here, CCL5 is linked to neoplasm.