Based on TCGA-KIRC RNA-seq and clinical data, ZNF582-AS1 expression was downregulated in ccRCC tissues compared with in the adjacent normal renal tissues (Fig. 1a), and lower ZNF582-AS1 expression was associated with advanced tumor stage, higher pathological stage, distant metastasis, and shorter OS (Overall Survival) and DFS (Disease Free Survival) (Fig. 1b). Here, ZNF582 is linked to neoplasm.