ZNF582 and nonpapillary renal cell carcinoma: In addition, our MSP and Sequenom MassARRAY results confirmed the hypermethylation status of ZNF582-AS1 in ccRCC tissues and cells, and treatment with 5-Aza and TSA induced demethylation of the ZNF582-AS1 promoter and increased ZNF582-AS1 expression.