Genetic screening in a group of 62 IBD children with disease onset before the age of 2 years revealed 5 (8%) cases of Il-10 or Il-10R genes’ mutations i.e., 2 (3.2%) with Il-10 gene mutation, 2 (3.2%) with Il-10RB gene mutation and 1 (1.6%) with Il-10RA gene mutation [31]. Here, IL10 is linked to inflammatory bowel disease.