To investigate whether the absence of EpCAM in Slug-overexpressing cells is involved in Slug mediating EMT and cell motility in cervical cancer cells, EpCAM expression was rescued via transient transfection of an EpCAM recombinant plasmid in Slug-overexpressing cells and CaSki-shCtr cells. The gene discussed is SNAI2; the disease is cervical carcinoma.