As meta-regression result indicated that publication year, NPC or control size, control sources, detection method, cutoff value, and article language are not the DOR heterogeneity of EBV-DNA, VCA-IgA, EBNA1-IgA and Rta-IgG, whereas detection method was possible DOR heterogeneity sources for the EA-IgA (P < 0.0095). The gene discussed is CD79A; the disease is nasopharyngeal carcinoma.