After 32 cycles, there was complete resolution of haemolytic anaemia (haemoglobin 13.7 g/dL, haematocrit 41.8 %, and haptoglobin 119 mg/dL), thrombocytopaenia (platelet count 149,000/μL), and azotaemia (blood urea nitrogen 13.0 mg/dL, serum creatinine 1.10 mg/dL). This evidence concerns the gene HP and non-autoimmune hemolytic anemia.