HSPA6 was also found to be overexpressed in human HCC tissues and a potential risk factor for HCC reccurence.29 We found that the expression of HSPA6 increased with methylation around rs57711775, which could mean that methylation potentially plays a role in upregulating HSPA6. Furthermore, the A allele of rs57711775 that is associated with higher HSPA6 expression and higher methylation in our analysis. Here, HSPA6 is linked to hepatocellular carcinoma.