CXCL1 and infection: Since IL-1β, CXCL1, and CXCL2 drive phagocyte recruitment during skin infection [52] and iKIR enhances the abundance of these mediators at days 1 and 3 after infection (Figs 3B and S2B), we aimed to investigate whether iKIR treatment increases neutrophil and/or monocyte-derived macrophage migration to the site of infection.