Recent work showed that Mycobacterium tuberculosis survived in Nox2-KO macrophages, and high levels of ROS induced via NOX2 were correlated with more favorable tuberculosis treatment outcome [60] Moreover, another recent study showed that a genetic variation in NCF2, a Nox2 complex activator, contributes to the susceptibility to tuberculosis in a Chinese population [61]. The gene discussed is NCF2; the disease is tuberculosis.