The recruited individuals were eligible for booster vaccinations with Tdap, containing tetanus toxoid (T), diphtheria toxoid (d), and acellular Pertussis (aP: filamentous hemagglutinin [FHA], fimbriae 2/3 [Fim2/3], pertactin [PRN], and inactivated pertussis toxin [PT]) antigens. This evidence concerns the gene CSF1R and pertussis.