CD274 and neoplasm: Furthermore, when we compared the expression levels of PDL1 at the per-cell level within each cell type cluster (i.e., cell states instead of cell type abundances), the top 2 CD45– cell clusters, annotated as Tumor 1 and Tumor 2, showed substantial and statistically significant differences in PDL1 expression, again showing that MC38 tumors have higher PDL1 expression within the CD45– compartment (Figure 5B).