To further dissect the contribution of macrophage-expressed FABP4 in autoimmune destruction of β cells and diabetes, we next performed adoptive transfer experiments by transplantation of FABP4–/– and FABP4+/+ bone marrow (BM)into FABP4+/+NOD and FABP4–/–NOD mice, respectively (Figure 7A). The gene discussed is FABP4; the disease is diabetes mellitus.