CD4 and diabetes mellitus: In line with previous reports (29–32), adoptive transfer of both diabetogenic CD4+ T and CD8+ T cells from both types of donor mice (FABP4–/–NOD and FABP4+/+NOD mice) into FABP4–/–NOD mice accelerated the development of autoimmune diabetes, as evidenced by much earlier onset and higher incidence of diabetes compared with FABP4–/–NOD mice treated with vehicle control (Supplemental Figure 6E).