In contrast, transplantation of FABP4+/+ BM into FABP4–/–NOD mice significantly increased the incidence of diabetes (71.86% vs. 51.79%) and aggravated insulitis, β cell apoptosis, inflammation, and activation of autoreactive T cells compared with FABP4–/–NOD mice transplanted with FABP4–/– BM (Figure 7). The gene discussed is FABP4; the disease is diabetes mellitus.