CHRNA4 and autosomal dominant nocturnal frontal lobe epilepsy: Autosomal dominant sleep‐related hypermotor epilepsy (ADSHE: previously known as autosomal dominant nocturnal frontal lobe epilepsy [ADNFLE]) is a subfamily of sleep‐related hypermotor epilepsy syndrome (SHE), the first genetic epilepsy identified to be caused by a mutation in CHNRA4, the gene for the α4 subunit of the nAChR, as described in 1994 (Scheffer et al., 1994; Tinuper et al., 2016).