The increased expression of SSRP1 was positively correlated with the expression of Treg and T cell exhaustion markers (CCR8, CTLA4, FOXP3, GZMB, HAVCR2, LAG3, PDCD1, STAT5B, and TGFB1) in HCC. The gene discussed is TGFB1; the disease is hepatocellular carcinoma.