It is considered a public health problem with approximately 425 million cases registered in 2017, with a growth estimate of 629 million adults by 2045.(1) The most common is type 2 diabetes mellitus (DM2), representing 90 to 95% of cases, characterized by a deficiency in insulin action/production and insulin resistance, with advanced age, obesity, lack of physical activity, and family history as the risk factors for its development.(2). Here, INS is linked to diabetes mellitus.