Table 1 presents the demographic and biochemical baseline characteristics, and thecontrolled ovarian stimulation (COS) outcome of PCOM patients with and without ovarianhyper-response. Hyper-response after COS was defined as retrieved oocyte numbers >15 and/orooestradiol level on the triggering day >3500 pg/ml. In total, 41% (n=41) of the PCOMpatients met the criteria for ovarian hyper-response. There were no cases of moderate,severe or critical OHSS according to the GnRH antagonist/agonist triggered/freeze allprotocol and Navot’s criteria (22). Here, GNRH1 is linked to ovarian hyperstimulation syndrome.