Patients with lupus nephritis carrying C alleles on STAT4, position rs7582694 were at higher risk of class III kidney injury (OR 11.4); 13 times more likely to develop class IV‐S and 8.9 times to develop renal lesion class IV‐G compared with patients without the allele, the differences were statistically significant with p < 0.05 (Table 3). The gene discussed is STAT4; the disease is injury.