In regard to potential relevance to COVID‐19, Nln is the only other peptidase, in addition to ACE and neprilysin that has been linked to both inactivation of these three vasoactive peptides (bradykinin, substance P, and neurotensin) and microvascular permeability, edema formation, neuroinflammation, and stroke. The gene discussed is TAC1; the disease is COVID-19.