The original hypotheses proposed by van de Veerdonk et al. (van de Veerdonk et al., 2020) and Roche and Roche (Roche & Roche, 2020), and subsequent preliminary experimental confirmation and proposed mechanistic model by Garvin and colleagues (Garvin et al., 2020) placing bradykinin, that is, “bradykinin storm” hypothesis, in the center of COVID‐19 pathology is scientifically intriguing and important for better understanding of this complex disease. The gene discussed is KNG1; the disease is COVID-19.