Present studies on HMOX1 are mainly focused on the oxidative stress and hypoxic injury, such as the research by Synowiec et al., on the involvement of HMOX1 in the oxidative stress process in age-related macular degeneration [31], and the investigation by Cordova et al. on the relationship between HMOX1 and systemic lupus erythematosus in children [32]. The gene discussed is HMOX1; the disease is systemic lupus erythematosus.