APOB and atherosclerosis: In present study we investigate possible associations of KATP variants with the risks of increased Apo B serum levels (≥ 80 mg/dL) and ASCVD (e.g., CAS ≥ 50% and new-onset IS) in South China, and identify the plasma expression profile of exo-miRs among subjects under specific genotype (KATP variants)-phenotype (Apo B ≥ 80 mg/dL) correlations.