Patients with A/C haplotype (dominant genetic model) had higher SLEDAI score [OR 1.119, CI 95% (1.015–1.234), p = 0.024] while those with the same haplotype, but in the recessive model (ACAC), had higher frequency of anti-dsDNA positivity [OR 3.026, CI 95% (1.062–8.624), p = 0.038], anti-U1RNP positivity [OR 5.649, CI 95% (1.199–26.610), p = 0.029], and nephritis [OR 2.501, CI 95% (1.004–6.229), p = 0.049]. Here, SNRNP70 is linked to nephritis.