We hypothesised that perhaps the requirement for WDR73 in UsnRNA processing was cell type dependent, and therefore compared levels of unprocessed mRNA transcripts encoding U1, U2, U4 and U12 in two NPC lines derived from induced pluripotent stem cells (iPSCs) obtained from a GAMOS patient with the c.129C > G WDR73 mutation and in two unrelated control NPC lines. Here, WDR73 is linked to nasopharyngeal carcinoma.