Out of 1242 breast cancers in stages 0, I or II, intrinsic subtype was established in 1152 cases; luminal A-like was the most frequent subtype (687 cases, 60%), 324 cases (28%) were luminal B-like, 52 (5%) were HER2 (non-luminal) and 89 (8%) were triple negative. The gene discussed is ERBB2; the disease is breast carcinoma.