Factors associated with lower probability of being treated Over St Gallen were age (RRR = 0.70, 95% CI 0.62–0.81 for each 10 years more), poorly differentiated cancers (RRR = 0.09, 95% CI 0.04–0.19), HER2 positive cancers (RRR = 0.46, 95% CI 0.26–0.81) and luminal B and triple negative subtypes (RRR = 0.07, 95% CI 0.04–0.13 and RRR = 0.03, 95% CI 0.01–0.11, respectively). The gene discussed is ERBB2; the disease is cancer.