Galectin-3 level had a strong association with poor stroke prognosis and unadjusted and adjusted risk increased 25% (OR, 1.25; 95%CI, 1.17-1.33; P<0.001) and 14% (OR, 1.14; 95%CI, 1.07-1.22; P<0.001), respectively for per unit(ng/ml) level increasing. This evidence concerns the gene LGALS3 and stroke disorder.