On the other hand, GO terms enriched in mEPN cells converged to Glioma, PI3K-Akt signaling pathway, Signaling by PDGF, VEGF signaling pathway, RNA Polymerase II Transcription, Protein processing in the endoplasmic reticulum, and non-integrin membrane-ECM interactions (Fig. 6b; Additional file 12: Table S4B). The gene discussed is AKT1; the disease is central nervous system cancer.