Therefore, to examine if blockade of these signaling pathways had a significant inhibitory effect on the tumor growth, we performed an anti-cancer drug screening using the FDA-approved drug library with additional selected-NF-κB inhibitors in two mEPN cells (Additional file 3: Fig. S2A; Additional file 13: Table S5A) [40]. The gene discussed is NFKB1; the disease is neoplasm.