ZBTB18 and neoplasm: It has been reported that Zinc Finger and Broad complex, Tramtrack, Bric_a brac (BTB) Domain Containing 18 (ZBTB18/ZNF238) is a zinc finger transcriptional repressor that belongs to the BTB or poxvirus and zing finger (POZ)-zinc finger (BTB/POZ-ZF) protein family involving in brain development and neuronal differentiation [23, 24]; ZBTB18 serves as a tumor suppressor in glioblastoma [25, 26].