However, current evidence suggests that EGFR Exon 20ins tend to be mutually exclusive with other common NSCLC mutation types including other EGFR mutations and mutations in KRAS, BRAF, HER2, NRAS, PIK3CA, MAP2K1/MEK1, AKT, as well as ALK rearrangements [4, 57, 58]. Here, MAP2K1 is linked to non-small cell lung carcinoma.