However, current evidence suggests that EGFR Exon 20ins tend to be mutually exclusive with other common NSCLC mutation types including other EGFR mutations and mutations in KRAS, BRAF, HER2, NRAS, PIK3CA, MAP2K1/MEK1, AKT, as well as ALK rearrangements [4, 57, 58]. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.