The IL-6 -572G/C polymorphism was also exhibited significant association with the increasing risk of stomach cancer under four genetic models [C vs. G: OR = 1.16, 95% CI = 1.03–1.30, p-value = 0.0069; CC vs. GG: OR = 1.41, 95% CI = 1.10–1.81, p-value = 0.0076; CC vs. CG + GG: OR = 1.29, 95% CI = 1.07–1.55, p-value = 0.0080; CC + CG vs. GG: OR = 1.41, 95% CI = 1.09–0.81, p-value = 0.0088] and lung cancer for genetic models [CC + CG vs. GG: OR = 1.31, 95% CI = 1.04–1.65, p-value = 0.0228; CG vs. CC + GG: OR = 1.31, 95% CI = 1.08–1.59, p-value = 0.0072]. This evidence concerns the gene IL6 and gastric neoplasm.