YTHDF2 and glioma: To verify that the effect of miR-145 on m6A RNA methylation and induction of nascent translation is specific for transcripts where miR-145 binds within the m6A peak, like CLIP3, we determined the effect of the miR-145 antagomir on nascent translation of YTHDF2, which is a transcript that is expressed in human glioma cells (Fig F in S1 Text), has conserved binding sites for miR-145 at the 3’-UTR (www.targetscan.org) and is not m6A RNA demethylated during differentiation of GSCs.