UBE2R2 and neoplasm: To show that the recruitment of FTO is not specific to miR-145 but rather a mechanism that RRACH-binding miRNAs employ for regulation of their targeted mRNAs, we performed FTO RIPs after overexpression of the other two tumor-suppressive miRNAs miR-143 and miR-129 (Fig 3B) followed by qPCR of their target genes UBE2R2 and ATN1 respectively.