The MOD value of PAI-1 staining of the glandular epithelium in the ectopic endometrium with adenomyosis was significantly stronger than that in the eutopic endometrium with adenomyosis and the normal endometrium without adenomyosis (for the proliferative phase, both 푃 < 0.0001; for the secretory phase, 푃<0.0001 and 푃=0.0001, respectively) (Fig. 1b and c). The gene discussed is SERPINE1; the disease is adenomyosis.