Data from the discovery data demonstrated that a higher proportion of IFN-γ response-DN, IFN-β biosynthetic process, regulation of IFNA signaling, negative regulation of IFN-γ secretion, IFNG pathway, response to IFNG-DN, negative regulation of response to IFN-γ, type 1 IFN biosynthetic process, and positive regulation of IFNα production etc. was observed in asthma group than in healthy control group (all P-values <0.05) (Figure 1). This evidence concerns the gene IFNB1 and asthma.