IFNA1 and asthma: In our study, we first explored the role of 74 IFN signatures in blood specimens of patients with asthma and observed that five IFN signatures (IFN-γ response-DN, negative regulation of IFN-γ secretion, IFNG pathway, negative regulation of response to IFN-γ, and type 1 IFN biosynthetic process) exhibited a higher level in asthma group than in healthy control group.