UM patients were in order with the risk score increasing and patients with higher risk were associated with lower DLC1, GABARAPL1, LMCD1, PRKCD, TUSC1 expressions, higher BNIP1, ITGA6 IKBKE and FKBP1A expressions, more Chr3/Chr8q loss, less Chr6p loss and higher tumor thickness, diagnostic age and clinical stage (Figure 2G). The gene discussed is ITGA6; the disease is neoplasm.