The effect remained significant for both ADem (OR = 1.29, 95% CI = 1.08–1.53, p = 4.5×10–3) and VaD (OR = 2.17, 95% CI = 1.74–2.69, p = 1.9×10–12) when APOE status, triglycerides, and diagnoses of hypercholesterolemia, hypertension, and diabetes were included in the model as covariates. This evidence concerns the gene APOE and hypertensive disorder.