After combination of the expression pattern and survival analysis, eight upregulated hub gens (CCNB1, BUB1, CDK1, AURKB, KIF11, PBK and NUSAP1) stood out with dramatical upregulation in cervical cancer and were significantly correlated with good prognosis of cervical cancer (P < 0.05, Figure 3(a)). The gene discussed is PBK; the disease is cervical cancer.