In the previous reports, CYP2J2 is a major isoform responsible for the metabolism of endogenous PUFAs, particularly, previous studies also indicated that it exhibited a significant increase expression in various carcinoma cell lines and could promote proliferation and protect the cells against apoptosis, all of which leads to the inhibition of CYP2J2 became a new therapeutic target for various cancers9,.13 Here, CYP2J2 is linked to carcinoma.