INS and isolated hemihyperplasia: According to the literature (Drager et al., 2015; Muhl & Pfeilschifter, 2003; Murphy et al., 2017; Thomas et al., 2017) and although body weight and fasting blood glucose were similar to normoxic mice, low‐fat diet mice exposed to chronic IH exhibited common features of systemic insulin resistance, such as increased fasting plasma insulin levels and impaired insulin sensitivity during ITT.