Furthermore, though the three isoforms of TGF‐β exhibit significant sequence homology (71%–79% identity, Figure 1A), they have opposite effects on fibrosis disease progression, with TGF‐β1 promoting fibrosis while TGF‐β3 having anti‐fibrotic effect.1, 2, 6, 12. Here, TGFB1 is linked to fibrosis.