MBL2 and rheumatoid arthritis: These important functional activities explain why the defect in MBL has been shown to be associated with different infectious diseases such as malaria, human immunodeficiency virus (HIV) infection, leprosy, leishmaniasis, schistosomiasis, trypanosomiasis, tuberculosis, systemic lupus erythematosus, rheumatoid arthritis, recurrent vulvovaginal infections (RVVI), filariasis, etc. [51,52,53,54,55,56,57,58].