Additionally, abnormal expression of TMEM16A was found in human lung adenocarcinoma (Jia et al., 2015), ovarian cancer(Liu et al., 2019), acinar cell carcinoma (Chenevert et al., 2012)and pancreatic ductal carcinoma (Sauter et al., 2015; Mazzone et al., 2012). Here, ANO1 is linked to pancreatic ductal adenocarcinoma.