Regarding innate immunity, SARS-CoV-2 infection of enterocytes was found to induce a strong IFN response and the production of cytokines (e.g., the IFNγ-inducible cytokine CXCL10 known to bind CXCR3 receptor and to induce inflammation) (97), similar to that observed during infection of respiratory tissues (196). This evidence concerns the gene IFNA1 and infection.