Mutant p53 induces VEGF expression through forming a complex with the lncRNA MALAT1 to promote the chromatin association of MALAT1, leading to recruitment of MALAT1 on VEGFA pre-mRNA to enhance its pro-angiogenic isoform expression in breast cancer cells (Pruszko et al., 2017). The gene discussed is MALAT1; the disease is breast carcinoma.