Inflammatory factors CCRL1 (called ACKR4) (Ulvmar et al., 2014), transcription factor PU.1 (Yashiro et al., 2019), and IL-18-driven human helper NK cells (Wong et al., 2014) participated in the regulation of DC migration, which may contribute to adaptive immune responses that are associated with infection, cancer, or vaccination. The gene discussed is ACKR4; the disease is cancer.