In addition, some representative oncogenic features, such as PI3K signaling, epithelial–mesenchymal transition, and angiogenesis were statistically enriched in Mettl3 conditional knockout (KO) mice, elucidating that Mettl3 might regulate BCa in the aspect of oncogenesis, metastasis, and tumor angiogenesis-mediated chemoresistance (Figures 4D–F). The gene discussed is METTL3; the disease is neoplasm.